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Articles (39)
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Picornavirus non-structural proteins as targets for new anti-virals with broad activity

Heléne Norder, Armando M. De Palma, Barbara Selisko, Lionel Costenaro, Nicolas Papageorgiou, Carme Arnan, Bruno Coutard, Violaine Lantez, Xavier De Lamballerie, Cécile Baronti, Maria Solà, Jinzhi Tan,

Journal:

Antiviral Research

Année:

2011

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2011

The viral RNA capping machinery as a target for antiviral drugs

François Ferron, Etienne Decroly, Barbara Selisko, Bruno Canard

Journal:

Antiviral Research

Année:

2012

Langue:

english

Fichier:

PDF, 1001 KB

english, 2012

Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives

Coutard, Bruno, Barral, Karine, Lichière, Julie, Selisko, Barbara, Martin, Baptiste, Aouadi, Wahiba, Lombardia, Miguel Ortiz, Debart, Françoise, Vasseur, Jean-Jacques, Guillemot, Jean Claude, Canard,

Journal:

Journal of Virology

Année:

2017

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2017

Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

Selisko, Barbara, Papageorgiou, Nicolas, Ferron, François, Canard, Bruno

Journal:

Viruses

Année:

2018

Langue:

english

Fichier:

PDF, 5.07 MB

english, 2018

Antibody BCF2 against scorpion toxin cn2 from Centruroides noxius hoffmann: Primary structure and three-dimensional model as free fv fragment and complexed with its antigen

Barbara Selisko, Alexei F. Licea, Baltazar Becerril, Fernando Zamudio, Lourival D. Possani, Eduardo Horjales

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1999

Langue:

english

Fichier:

PDF, 658 KB

english, 1999

Invertase-catalyzed reactions in alcoholic solutions

Barbara Selisko, Renate Ulbrich, Alfred Schellenberger, Ute Müller

Journal:

Biotechnology and Bioengineering

Année:

1990

Langue:

english

Fichier:

PDF, 350 KB

english, 1990

Soluble and immobilized enzymes in water-miscible organic solvents: glucoamylase and invertase

Renate Ulbrich-Hofmann, Barbara Selisko

Journal:

Enzyme and Microbial Technology

Année:

1993

Langue:

english

Fichier:

PDF, 841 KB

english, 1993

Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′O)-methyltransferase

Victor B. Luzhkov, Barbara Selisko, Anneli Nordqvist, Frédéric Peyrane, Etienne Decroly, Karine Alvarez, Anders Karlen, Bruno Canard, Johan Åqvist

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 880 KB

english, 2007

Corrigendum to “Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′O)-methyltransferase” [Bioorg. Med. Chem. 15 (2007) 7795–7802]

Victor B. Luzhkov, Barbara Selisko, Anneli Nordqvist, Frédéric Peyrane, Etienne Decroly, Karine Alvarez, Anders Karlen, Bruno Canard, Johan Åqvist

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 69 KB

english, 2008

Mapping of an epitope recognized by a neutralizing monoclonal antibody specific to toxin Cn2 from the scorpion Centruroides noxius, using discontinuous synthetic peptides

Emma S. Calderon-Aranda, Barbara Selisko, Eunice J. York, Georgina B. Gurrola, John M. Stewart, Lourival D. Possani

Journal:

FEBS Journal

Année:

1999

Langue:

english

Fichier:

PDF, 647 KB

english, 1999

Structure and function of scorpion toxins affecting K+-channels

Lourival D. Possani, Barbara Selisko, Georgina B. Gurrola

Journal:

Perspectives in Drug Discovery and Design

Année:

1999

Langue:

english

Fichier:

PDF, 153 KB

english, 1999

Structural bases for substrate recognition and activity in Meaban virus nucleoside-2′-O-methyltransferase

Eloise Mastrangelo, Michela Bollati, Mario Milani, Barbara Selisko, Frederic Peyrane, Bruno Canard, Gilda Grard, Xavier de Lamballerie, Martino Bolognesi

Journal:

Protein Science

Année:

2007

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2007

Substituted Imidazopyridines as Potent Inhibitors of Hepatitis C Virus Replication that Target the Viral Polymerase

Inge Vliegen, Jan Paeshuyse, Laura S. Lehman, Weidong Zhong, Sofie Roofthooft, Hélène Dutartre, Barbara Selisko, Bruno Canard, Nina Boddeker, Steven Bondy, David Oare, Erik De Clercq, William A. Lee,

Journal:

Antiviral Research

Année:

2007

Langue:

english

Fichier:

PDF, 128 KB

english, 2007

The flavivirus polymerase as a target for drug discovery

Hélène Malet, Nicolas Massé, Barbara Selisko, Jean-Louis Romette, Karine Alvarez, Jean Claude Guillemot, Hughes Tolou, Thai Leong Yap, Subash G. Vasudevan, Julien Lescar, Bruno Canard

Journal:

Antiviral Research

Année:

2008

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2008

Flaviviral methyltransferase/RNA interaction: Structural basis for enzyme inhibition

Mario Milani, Eloise Mastrangelo, Michela Bollati, Barbara Selisko, Etienne Decroly, Mickaël Bouvet, Bruno Canard, Martino Bolognesi

Journal:

Antiviral Research

Année:

2009

Langue:

english

Fichier:

PDF, 816 KB

english, 2009

3′,5′di-O-Trityluridine Inhibits Flavivirus (Dengue and Yellow Fever Virus) Replication and Targets the Viral RNA Dependent RNA Polymerase

Tine De Burghgraeve, Suzanne J.F. Kaptein, Kai Dallmeier, Barbara Selisko, Michael Jacobs, Bruno Canard, Arthur Van Aerschot, Johan Neyts

Journal:

Antiviral Research

Année:

2011

Langue:

english

Fichier:

PDF, 72 KB

english, 2011

The RNA helicase, nucleotide 5′-triphosphatase, and RNA 5′-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core

Delphine Benarroch, Barbara Selisko, Giada A. Locatelli, Giovanni Maga, Jean-Louis Romette, Bruno Canard

Journal:

Virology

Année:

2004

Langue:

english

Fichier:

PDF, 942 KB

english, 2004

Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases

Barbara Selisko, Hélène Dutartre, Jean-Claude Guillemot, Claire Debarnot, Delphine Benarroch, Alexander Khromykh, Philippe Desprès, Marie-Pierre Egloff, Bruno Canard

Journal:

Virology

Année:

2006

Langue:

english

Fichier:

PDF, 907 KB

english, 2006

Cobatoxins 1 and 2 from Centruroides noxius Hoffmann constitute a subfamily of potassium-channel-blocking scorpion toxins

Barbara Selisko, Consuelo Garcia, Baltazar Becerril, Froylan Gómez-Lagunas, Carlos Garay, Lourival D. Possani

Journal:

FEBS Journal

Année:

1998

Langue:

english

Fichier:

PDF, 672 KB

english, 1998

An Insect-Specific Toxin from Centruroides noxius Hoffmann : cDNA, Primary Structure, Three-Dimensional Model and Electrostatic Surface Potentials in Comparison with Other Toxin Variants

Barbara Selisko, Consuelo Garcia, Baltazar Becerril, Muriel Delepierre, Lourival D. Possani

Journal:

FEBS Journal

Année:

1996

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1996

Crystal Structure and Activity of Kunjin Virus NS3 Helicase; Protease and Helicase Domain Assembly in the Full Length NS3 Protein

Eloise Mastrangelo, Mario Milani, Michela Bollati, Barbara Selisko, Frederic Peyrane, Vittorio Pandini, Graziella Sorrentino, Bruno Canard, Peter V. Konarev, Dmitri I. Svergun, Xavier de Lamballerie,

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2007

Structural and Functional Analysis of Methylation and 5′-RNA Sequence Requirements of Short Capped RNAs by the Methyltransferase Domain of Dengue Virus NS5

Marie-Pierre Egloff, Etienne Decroly, Hélène Malet, Barbara Selisko, Delphine Benarroch, François Ferron, Bruno Canard

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2007

Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus

Michela Bollati, Mario Milani, Eloise Mastrangelo, Stefano Ricagno, Gabriella Tedeschi, Simona Nonnis, Etienne Decroly, Barbara Selisko, Xavier de Lamballerie, Bruno Coutard, Bruno Canard, Martino Bol

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2009

Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann

Barbara Selisko, Gabriela Cosı́o, Consuelo Garcı́a, Baltazar Becerril, Lourival D Possani, Eduardo Horjales

Journal:

Toxicon

Année:

2004

Langue:

english

Fichier:

PDF, 185 KB

english, 2004

Isolation and structure–functional characterization of phage display library-derived mimotopes of noxiustoxin, a neurotoxin of the scorpion Centruroides noxius Hoffmann

Tatiana Gazarian, Barbara Selisko, Pascal Hérion, Karlen Gazarian

Journal:

Molecular Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 422 KB

english, 2000

Isolation, Characterization and Comparison of a Novel Crustacean Toxin with a Mammalian Toxin from the Venom of the Scorpion Centruroides noxius Hoffmann

Consuelo Garcı́a, Baltazar Becerril, Barbara Selisko, Muriel Delepierre, Lourival D. Possani

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Année:

1997

Langue:

english

Fichier:

PDF, 465 KB

english, 1997

Evaluation of Adamantane Derivatives as Inhibitors of Dengue Virus mRNA Cap Methyltransferase by Docking and Molecular Dynamics Simulations

Luzhkov, Victor, Decroly, Etienne, Canard, Bruno, Selisko, Barbara, Åqvist, Johan

Journal:

Molecular Informatics

Année:

2013

Langue:

english

Fichier:

PDF, 3.43 MB

english, 2013

3′,5′Di-O-trityluridine inhibits in vitro flavivirus replication

De Burghgraeve, Tine, Selisko, Barbara, Kaptein, Suzanne, Chatelain, Grégory, Leyssen, Pieter, Debing, Yannick, Jacobs, Michael, Van Aerschot, Arthur, Canard, Bruno, Neyts, Johan

Journal:

Antiviral Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2013

Regulation of Flavivirus RNA synthesis and replication

Selisko, Barbara, Wang, Chunling, Harris, Eva, Canard, Bruno

Journal:

Current Opinion in Virology

Année:

2014

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2014

A closed-handed affair: positive-strand RNA virus polymerases

Subissi, Lorenzo, Decroly, Etienne, Selisko, Barbara, Canard, Bruno, Imbert, Isabelle

Journal:

Future Virology

Année:

2014

Langue:

english

Fichier:

PDF, 2.36 MB

english, 2014

Comparison of dengue virus and HCV: from impact on global health to their RNA-dependent RNA polymerases

Potisopon, Supanee, Priet, Stéphane, Selisko, Barbara, Canard, Bruno

Journal:

Future Virology

Année:

2014

Langue:

english

Fichier:

PDF, 3.39 MB

english, 2014

The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family

van der Linden, Lonneke, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, De Palma, Armando M., Tanchis, Federica, Goris, Nesya, Lefebvre, Da

Journal:

PLoS Pathogens

Année:

2015

Langue:

english

Fichier:

PDF, 3.71 MB

english, 2015

Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome

Selisko, Barbara, Potisopon, Supanee, Agred, Rym, Priet, Stéphane, Varlet, Isabelle, Thillier, Yann, Sallamand, Corinne, Debart, Françoise, Vasseur, Jean-Jacques, Canard, Bruno, Diamond, Michael S.

Journal:

PLoS Pathogens

Année:

2012

Langue:

english

Fichier:

PDF, 2.38 MB

english, 2012

In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation

Bouvet, Mickaël, Debarnot, Claire, Imbert, Isabelle, Selisko, Barbara, Snijder, Eric J., Canard, Bruno, Decroly, Etienne, Buchmeier, Michael J.

Journal:

PLoS Pathogens

Année:

2010

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2010

Substrate selectivity of Dengue and Zika virus NS5 polymerase towards 2′-modified nucleotide analogues

Potisopon, Supanee, Ferron, François, Fattorini, Véronique, Selisko, Barbara, Canard, Bruno

Journal:

Antiviral Research

Année:

2017

Langue:

english

Fichier:

PDF, 10.43 MB

english, 2017

Stratégies de formation de la structure coiffe chez les virus à ARN

Bouvet, Mickaël, Ferron, François, Imbert, Isabelle, Gluais, Laure, Selisko, Barbara, Coutard, Bruno, Canard, Bruno, Decroly, Etienne

Journal:

médecine/sciences

Année:

2012

Langue:

french

Fichier:

PDF, 3.62 MB

french, 2012

Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites

Shannon, Ashleigh, Le, Nhung Thi-Tuyet, Selisko, Barbara, Eydoux, Cecilia, Alvarez, Karine, Guillemot, Jean-Claude, Decroly, Etienne, Peersen, Olve, Ferron, Francois, Canard, Bruno

Journal:

Antiviral Research

Année:

2020

Fichier:

PDF, 909 KB

2020

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

Shannon, Ashleigh, Selisko, Barbara, Le, Nhung-Thi-Tuyet, Huchting, Johanna, Touret, Franck, Piorkowski, GÃ©raldine, Fattorini, VÃ©ronique, Ferron, FranÃ§ois, Decroly, Etienne, Meier, Chris, Coutard,

Journal:

Nature Communications

Année:

2020

Fichier:

PDF, 1.77 MB

2020

Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro

Thames, Joy E., Waters, Charles D., Valle, Coralie, Bassetto, Marcella, Aouadi, Wahiba, Martin, Baptiste, Selisko, Barbara, Falat, Arissa, Coutard, Bruno, Brancale, Andrea, Canard, Bruno, Decroly, Eti

Journal:

Bioorganic & Medicinal Chemistry

Année:

2020

Fichier:

PDF, 1.78 MB

2020